Animal Models in Osteosarcoma

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Animal Models in Osteosarcoma

Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to rapidly develop pulmonary metastases. Despite clinical advances, patients with metastatic disease ...

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ژورنال

عنوان ژورنال: Frontiers in Oncology

سال: 2014

ISSN: 2234-943X

DOI: 10.3389/fonc.2014.00189